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Since the physiologically suitable pH at the BBB is seven.4, higher concentrations of L-lactate might be needed to inhibit MCT-mediated transportation of GHB across the BBB, compared with the intestine or kidneys wherever a decreased physiological pH represents a driving power for absorption or reabsorption, respectively.The management of GHB overd

This is the preview of membership content material, log in through an institution to check accessibility. Accessibility this article), which routinely estimates the initial parameters for the selected versions and makes use of the Levenberg–Marquardt algorithm to determine the parameter values. The best design was determined using Akaike’s info